RESEARCH

We are a neurobiology lab interested in studying assembly and function of primary cilia – specialized signaling organelles present on almost all cells in the human body. Primary cilia are required for development, and defects in cilia assembly cause multisystemic genetic disorders called ciliopathies. We use genetics, molecular biology, and high-resolution imaging in two powerful model organisms (C. elegans and D. melanogaster) as well as mammalian cells to uncover novel signaling mechanisms of cilia assembly and decipher the role of cilia in neuronal function.